Copy Number Variants
Derek M. BickhartThis volume offers detailed step-by-step instructions to allow beginners and experts alike to run appropriate copy number variants (CNV) detection software on a dataset of choice and discern between false positive noise and true positive CNV signals. Chapters guide readers through single nucleotide polymorphism (SNP) chips, optical mapping assembly techniques, and current open-source programs specializing in CNV detection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Copy Number Variants: Methods and Protocols aims to provide guidance to Bioinformaticians and Molecular Biologists who are interested in identifying copy number variants (CNV) with a wide variety of experimental media种类:
年:
2018
出版:
1st ed.
出版社:
Springer New York;Humana Press
语言:
english
ISBN 10:
149398666X
ISBN 13:
9781493986668
系列:
Methods in Molecular Biology 1833
文件:
PDF, 6.48 MB
IPFS:
,
english, 2018